Insudex reader package deal 
is the world’s first and only rapid test for the early detection of type 1 diabetes and LADA (Latent Autoimmune Diabetes in Adults).
- Minimally invasive (capillary test)
- Easy to use
- Quick result (15 min)
For professional use: 20 pcs/pack.
GAD, GAD65 autoantibodies* against GAD (GADA), like IAA, are predictive of the risk of developing type 1 diabetes. GAD autoantibodies are present in the majority of adult patients with autoimmune diabetes. GAD autoantibodies are most common in people with type 2 diabetes, which also has an autoimmune component.
Early detection of type 1 diabetes
Autoimmune type 1 diabetes is preceded by a preclinical period, which is characterized by the appearance and presence of autoantibodies in individual cells. For children, the number of these autoantibodies is a better predictor of disease risk than the presence of a single autoantibody.
Correct diagnosis of LADA
Adults with presumed type 2 diabetes have autoantibodies in individual cells, which are characteristic of type 1 diabetes in children. This “mixed” form of diabetes is called LADA, type 1.5 diabetes or double diabetes.
Who should be tested?
Children with suspected common type 1 diabetes and their siblings.
Children or adolescents who present with suspected type 2 diabetes, but may in fact have type 1 diabetes. This is a group that cannot be distinguished without autoantibody screening and can benefit greatly from different tests.
Adults suspected of having type 1 diabetes, as a significant proportion of type 1 patients are diagnosed as adults.
Patients with established diabetes or pre(type-2) diabetes, where the presence of autoantibodies in addition to insulin resistance may predict a faster progression to insulin deficiency.
Diabetic patients who have autoimmune complications such as celiac disease or autoimmune thyroid disease.
Pregnant women with suspected gestational diabetes who may have undiagnosed type 1 diabetes.
How to perform tests
The test is performed by capillary sampling, where the blood is mixed with a buffer solution, which is then dripped directly onto the test. When the analysis is complete, a control line will appear at “C” if the test was performed correctly. If the test is positive (antibodies are present), a line appears next to the “T”. Further investigation should then be carried out to ensure the diagnosis of type 1 diabetes.
If you want to see the amount of antibodies, you insert the test cassette into the Insudex meter, which is purchased separately. The device then reads the measured value and a result is reported on the display or on a smartphone or tablet. Befor a first screening this is not necessary, but it can be good to know the amount of antibodies in many cases anyway.
Specifications
Limit value: 29 IU/ml
Sensitivity: 88%
Specificity: 98%
PPV**: 95%
NPV***: 94%
For more info, read more here (English): SV Insudex® Early detection brochure
*Autoantibodies are antibodies that the body forms against its own tissues or systems (antigens). Presence of autoantibodies is a sign of an autoimmune disease.
**Positive Predictive Value
***Negative Predictive Value
